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Cytokeratin 1 anticorps (pan) (FITC)

Cet anticorps anti-Cytokeratin 1 est un anticorps Souris Monoclonal détectant Cytokeratin 1 dans FACS, ICC et IF. Adapté pour Humain, Rat, Souris, Boeuf (Vache), Lapin, Poulet, Singe et Porc.
N° du produit ABIN5540281

Aperçu rapide pour Cytokeratin 1 anticorps (pan) (FITC) (ABIN5540281)

Antigène

Voir toutes Cytokeratin 1 (KRT1) Anticorps
Cytokeratin 1 (KRT1) (Keratin 1 (KRT1))

Reactivité

  • 101
  • 56
  • 52
  • 23
  • 16
  • 13
  • 7
  • 7
  • 6
  • 4
  • 3
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
Humain, Rat, Souris, Boeuf (Vache), Lapin, Poulet, Singe, Porc

Hôte

  • 77
  • 49
  • 1
Souris

Clonalité

  • 70
  • 57
Monoclonal

Conjugué

  • 54
  • 16
  • 7
  • 6
  • 4
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Cet anticorp Cytokeratin 1 est conjugé à/à la FITC

Application

  • 86
  • 52
  • 49
  • 27
  • 27
  • 26
  • 24
  • 19
  • 18
  • 17
  • 16
  • 10
  • 8
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Flow Cytometry (FACS), Immunocytochemistry (ICC), Immunofluorescence (IF)

Clone

AE1-AE3
  • Épitope

    • 19
    • 16
    • 16
    • 13
    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    pan

    Specificité

    AE 1/AE3 represents an excellent marker for distinguishing carcinomas from non-epithelial tumors reacts with all epithelium-derived tumors and their neoplasms. Decorates the majority of type I and type II keratins (formerly also designated cytokeratins). This antibody stains cytokeratins present in normal and abnormal human tissues and has shown high sensitivity in the recognition of epithelial cells and carcinomas. This antibody AE 1/AE 3 recognizes Low Molecular Weight Cytokeratins (CK 10 (56.5), CK14 (50), CK15 (50), CK16 (48) and CK19 (40) of the acidic family and CK1 (67), CK2 (65.5), CK3 (64), CK4 (59), CK5 (58) CK6 (56) and CK8 (52.5).

    Purification

    Protein A Chromatography

    Immunogène

    Human epidermal keratin.

    Isotype

    IgG1
  • Indications d'application

    Immunofluorescence: 10-20 μg /mL (1/10-1/20), incubate for 2 hours in the dark at RT or it can also be incubated overnight at 4 °C. Flow Cytometry: 0.2-1.0 μg/0.1 mL (1/200-1/1,000) (Not tested in our lab).

    Restrictions

    For Research Use only
  • Format

    Liquid

    Agent conservateur

    Sodium azide

    Précaution d'utilisation

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Stock

    4 °C,-20 °C

    Stockage commentaire

    Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. Shelf life: One year from despatch.
  • Antigène

    Cytokeratin 1 (KRT1) (Keratin 1 (KRT1))

    Autre désignation

    cytokeratin

    Sujet

    Cytokeratins are intermediate filament keratins found in the intracytoplasmic cytoskeleton of epithelial tissue There are two types of Cytokeratins: the low weight, acidic type I cytokeratins and the high weight, basic or neutral type II. Cytokeratins are usually found in pairs comprising a type I Cytokeratin and a type II cytokeratin. The high molecular weight cytokeratins, which are the basic or neutral cytokeratins, comprise subtypes CK1(67), CK2(65.5), CK3(64), CK4(59), CK5(58), CK6(56), CK7(54), CK8(52.5) and CK9. The low molecular weight cytokeratins, which are the acidic cytokeratins, comprise subtypes CK10 (56.5), CK12 (56), CK13 (53), CK14 (50), CK16 (48), CK17 (46), CK18 (45), CK19 (48) and CK20 (46).
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